87 Additional caution is required with any problem of polyiphragmia in the pharmacotherapy of the patients since a large number of medications could potentiate or reduce the therapeutic effects, or have adverse effects of each individual drug. Particular consideration should be taken of the antipsychotics polypharmacy. To enable an adequate and rational treatment, it is necessary to use Guides for the best clinical practices. The Home will introduce an individual treatment plan for each beneficiary, which will contain psycho-social rehabilitation programs, among other, related to occupational (work) therapy, group therapy, individual psychotherapy, sports activities and other. The Home will, when drafting the individual therapy plan of treatment, respect the will and preferences of beneficiaries, regardless their legal status. The data contained in the Records of injuries kept in the Home must correspond to the information the Home provided to the competent authorities, including the Regional Public Health Institute. The Home will make sure that the Records of injuries inflicted to beneficiaries, contain the data about the circumstances under which the injuries occurred (with reference to sources of data - anamnestic / heteroanemnestic), a detailed description of the established injuries, as well as the doctor‘s conclusion on the connection of the circumstances of the injuries and the identified injuries. The Home will maintain records of the deceased beneficiaries in the form of the Protocol of the deceased persons i.e. it will manage it so that at least the following data are recorded (ordinal year number, full names of the deceased’s parents, date of birth of the deceased, day and time of death, place of death, cause of death on the basis of the information entered in the death certificate form, information about whether the autopsy was requested, the full name of the doctor who performed the examination of the deceased and issued the death certificate, information on whether the autopsy was performed, and if so, by which institution, including the conclusion on the cause of death on the basis of autopsy, and the remarks). The doctors of the Home shall not issue death certificates for beneficiaries whose death occurred in the Home, but the Home will call the doctor of medicine designated within the territory of CM Aleksinac to provide expert determination of the time and cause of death. The Ministry of Labour, Employment, Veterans and Social Affairs will, in cooperation with relevant authorities, draw a Protocol on acting in the cases of unexpected (sudden) deaths of beneficiaries in social welfare institutions. The Home will conduct the mechanical restraint measure, or the so-called fixation, fully in compliance with the regulations and established standards of treatment of persons with mental disorders, and in particular: · measure of mechanical restraint against the beneficiary will be used exceptionally, when this is the only means to prevent the beneficiary to seriously harm his/her own life and safety and lives of other persons; · before applying a measure of mechanical restraint, it is necessary to consider and try to use a less restrictive measure;